heading
News
March, 2005

PathArt© is a comprehensive collection of manually curated information from literature as well as public domain databases on more than 1000 signaling and metabolic pathways.  PathArt© also provides a collection of 50000 components across 21 high priority disease states and 10 different physiologies with emphasis on pathway responsive genes, mutations and knockouts.

New Data Features:
    4000 interactions
    150 pathways
    1000 mutations
    500 knockouts

New Disease type:
    Ovarian cancer

New Physiologies: 

    Skeletal development
    Neurogenesis


New Software Features:

Interaction Maps Module including 50,000 protein-protein and protein small molecule interactions obtained by manual curation of abstracts and Full text literature.

Druggable Targets Module encompassing a coverage on  100 drugs with PK/PD, Toxicological data, Pharmacogenomics data across the disease types.

Protein Inhibitors Module with information on commercially available small molecule inhibitors for the proteins (130 well known inhibitors with 2D structure and other related information).

New Spring layout algorithm for Pathways with enhanced UI features to filter interactions based on mechanisms.

Export feature to export data into Resnet, SBML and PathXML formats.

 

 
APPS / RESEARCH TOOLS | SRM (Ordering / Data Retrieval) | TRAKIT | TRAINING | CAREERS
Hartwell Center home St. Jude home page