| first published March, 2005 |
PathArt Q4 New Release |
| first published January 2005 |
Installation of NWChem and Gamess |
| first published September 2004 |
CYANA speeds completion time... |
| first published September 2004 |
Installation of GridMathematica |
| first published August 2004 |
Vector NTI (9.0)-GenomeBench Patch-Windows version only A patch is avaiable for Vector NTI to correct a known issue with links in the GenomeBench application. Please click here to download the required file and for installation instructions. |
| first published July 2004 |
New DNA Analyzer = Lower Cost for DNA Sequencing & Genotyping The Hartwell Center's DNA Sequencing and Genotyping laboratory as purchased and tested a new Applied Biosystems 3730xl DNA Analyzer. This 96-capillary instrument is a replacement for one of our aging 3700's and will be used for both DNA sequence Analysis and for Genotyping. A second 3730xl is slated for purchase this year as well. These systems will increase our capacity to cope with a 30% increase in demand, they provide superb quality data, and they significantly lower the cost of analysis. As a result of these improvements, we are now reducing our sample analysis fee from $4/template to $1/template. |
| first published July 2004 |
New cDNA and Oligonucleotide Arrays Available
Microarrays (human CpG 12K chip) containing 12,192 CpG island clones from the Sanger Institute are now available at a cost of $100 per chip plus labeling costs. The CpG library was originally prepared by Sally Cross in the laboratory of Adrian Bird at the Wellcome Trust Centre for Cell Biology (University of Edinburgh). (...more) |
| first published July 2004 |
PathArt 2nd quarter update now available!
PathArt is a curated database of biomolecular interactions with tools for searching, analysis and visualization of data for use by microarray researchers and identification of potential drug targets. Important features include, coverage of over 896 regulatory and signaling pathways across species, browse pathways by organism, disease and other classifications, protein-protein interactions, information on knockout and mutagenesis studies, coverage of 17 high priority diseases and disease responsive genes, dynamic generation of pathway diagrams with highlighting based on expression level, and comprehensive information on all participating biomolecules curated from scientific journals and patents. It provides information and links to ten public domain databases like Unigene, LocusLink, OMIM, etc.
PathArt provides a plugin to allow direct access from the Spotfire application. A two-way access is provided to transfer data from Spotfire to PathArt and vice versa for further analysis.
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| first published January 2004 |
New! Hartwell Center Research Workshop Series |
first published
November 2003 |
St Jude ranked #251 in the 22nd TOP 500 List for Supercomputers
We are pleased to announce the successful installation, testing, benchmarking and deployment of a 280-processor Linux cluster (IBM BladeServer). This blade server provides St. Jude with significant computational horsepower to address cpu-intensive applications in bioinformatics, structural biology, and the Life Sciences here at St. Jude. This system achieved a maximum performance of 613.90 Gigaflops or 614 billion floating-point operations per second using the LinPack benchmark suite. St. Jude ranked #251on the Top500 Supercomputer list http://www.top500.org/list/2003/11 announced November 16th at the 22nd TOP500 list Conference in Phoenix.
Training in the use of the cluster has already been provided to 25 command-line users and is a prerequisite for any potential user. Contact Scott Malone, scott.malone@stjude.org, for training information. |
first published
August 2003 |
Update on 2-D gel Capabilities for Proteomics
Several improvements in the Hartwell Center 's 2-D gel electrophoresis service for proteomic analysis have been implemented during the last three months. The principal changes are as follows: (...more) |
first published
February 2003 |
Internet Connectivity Enhanced
The Hartwell Center's Operations group, AT&T, and ITS staff have completed phase 1 of an upgrade to our Internet connectivity that doubles our bandwidth and will increase redundancy and reliability. The new AT&T circuit provides us with one 20 megabit/sec circuit (Mps) burstable to 45 Mps. Phase 2 will provide a failover circuit of 2 Mps burstable to 45 Mps, one link to St. Louis and one to Atlanta. You may notice an increase in performance if you routinely download large datasets. Internet 2 connectivity remains at 100 Mps and is automatically used whenever you visit a web site on I2 (e.g. NCBI). |
first published
January 2003 |
Gene Expression Omnibus Submission Tool (GST)
Many scientific journals now require gene expression data be submitted to the Gene Expression Omnibus at the National Center for Biotechnology Information (NCBI) prior to publication. This process requires the collection of information from the Hartwell Center's Functional Genomics or CACT laboratories regarding the arrays and how they were processed, information regarding the design of the experiment, as well as the gene expression data itself. We have developed GST to simplify the assembly and packaging of this data for easy submission to GEO. To access GST go to http://hc-wlsprod.stjude.org/gst/gst |
first published
August 2002 |
Internet 2 Connectivity
We are now on Internet2; a high-speed network linking nearly 200 universities and research institutions (no commercial traffic) working in partnership with industry and government to develop and deploy advanced network applications and technologies, accelerating the creation of tomorrow's Internet. Internet2 is recreating the partnership among academia, industry and government that fostered today's Internet in its infancy. |
